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Long-actingInjections

Learn About
Injectable Medications

Long-acting injections (LAIs) are injectable antipsychotic medications that help control schizophrenia symptoms for a set amount of time. They gradually release into the body after they are injected and allow for longer periods of time between doses than a daily pill.

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Benefits of LAIs include

  • Increased adherence due to reduced need to take daily orals
  • Don’t have to take orals daily 
  • Medication levels stay steady in the blood for symptom control and a delay in episodes

Injections vs Oral

Injectable Treatments

Long-acting Injections

Long-acting injectable antipsychotic medications may be used to help manage acute psychotic episodes.

  • Are administered in a prescriber’s office, hospital, or in some states, a pharmacy setting
  • Get absorbed slowly into the body over time
  • Allow longer periods of time between doses

Oral Treatments

Tablets and Capsules

  • Need to be taken as prescribed by your provider
  • Come in varying doses
  • Can be taken directly by the patient (does not require healthcare professional administration)

Dissolvable Tablets

  • Use saliva to dissolve the medication for best absorption
  • May need to be taken more than 1 time a day
  • May need to be absorbed before eating or drinking

Oral Solutions

  • Liquid-based medications that are swallowed
  • May need to be taken more than 1 time a day
  • Require measuring with a dosing spoon, oral syringe, or dropper

A change in a schizophrenia treatment plan could make a difference

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Exploring Your Beliefs About Medication Worksheet

A worksheet that can help you become aware of your beliefs and understand them.

Learn About Injections FAQs

  • Who gives the injection to me?

    A doctor or trained healthcare professional gives the injection.

  • In what part of the body is the injection given?

    Usually, the injection is given in the muscle of the upper arm or buttocks.

  • Where would I have to receive a long-acting injection?

    Injections are given by a doctor or trained healthcare professional, typically in a medical office or a mental health clinic.

  • Is a long-acting injection for people who are sicker than people who take a daily pill?

    Not at all; it’s just a different way to take antipsychotic medication. Remember, a long-acting injection is different from the shots that are used in crisis situations like emergency room visits.

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What a once-monthly injection can offer

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You and your doctor know that your medication is in your system for 1 month

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After initiation, it’s only administered once a month, while a pill needs to be taken every day

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Helps delay another schizophrenia episode

Curious about a specific, once-monthly option for adults with schizophrenia?

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